Small molecules which reverse BACH2 KO
Canned Analysis
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General Information
AccessionDCA00022628
TitleSmall molecules which reverse BACH2 KO
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which reverse the gene expression signature induced by BACH2 KO in the thymocytes cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d223c1e467bea600fbb0fe
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis Curatorasingh
CREEDS IDgene:2778
Cell Typethymocytes
Gene Symbol (human)BACH2
Gene Symbol (mouse)Bach2
Organismmouse
Perturbation TypeKO
L1000CDS2 parameters
Directionreverse
Characteristic Direction parameters
Control SamplesGSM1045734, GSM1045735, GSM1045736
Perturbed SamplesGSM1045737, GSM1045738, GSM1045739
Tools used in the analysis
Dataset Accession
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE42598
Gene Expression Omnibus
Gene expression in Bach2-deficient and wildtype CD4 single-positive thymocytes from mixed chimeric animals
7
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