Small molecules which reverse DICER1 KO
Canned Analysis
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General Information
AccessionDCA00022718
TitleSmall molecules which reverse DICER1 KO
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which reverse the gene expression signature induced by DICER1 KO in the CD4+CD62L- resting T cells cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d237a0e467bea600fbb9c4
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis CuratorTolen
CREEDS IDgene:2791
Cell TypeCD4+CD62L- resting T cells
Gene Symbol (human)DICER1
Gene Symbol (mouse)Dicer1
Organismmouse
Perturbation TypeKO
L1000CDS2 parameters
Directionreverse
Characteristic Direction parameters
Control SamplesGSM1447410, GSM1447411, GSM1447412
Perturbed SamplesGSM1447413, GSM1447414, GSM1447415
Tools used in the analysis
Dataset Accession
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE59848
Gene Expression Omnibus
Expression data from Dicer WT and Dicer KO mouse CD4 T cells.
7
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