Small molecules which mimic BTK KO
Canned Analysis
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General Information
AccessionDCA00022735
TitleSmall molecules which mimic BTK KO
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which mimic the gene expression signature induced by BTK KO in the Splenic B-cells cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d21774e467bea600fbabcc
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis CuratorTolen
CREEDS IDgene:2833
Cell TypeSplenic B-cells
Gene Symbol (human)BTK
Gene Symbol (mouse)Btk
Organismmouse
Perturbation TypeKO
L1000CDS2 parameters
Directionmimic
Characteristic Direction parameters
Control SamplesGSM1303878, GSM1303879
Perturbed SamplesGSM1303876, GSM1303877
Tools used in the analysis
Dataset Accession
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE53946
Gene Expression Omnibus
Affymetrix gene expression of Transitional Type-1 B-cells from Wild-type (CBA), Xid and Btk KO mice
7
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