Small molecules which reverse MBD1 KO
Canned Analysis
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General Information
AccessionDCA00022740
TitleSmall molecules which reverse MBD1 KO
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which reverse the gene expression signature induced by MBD1 KO in the thymus cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d22788e467bea600fbb2aa
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis CuratorTolen
CREEDS IDgene:2835
Cell Typethymus
Gene Symbol (human)MBD1
Gene Symbol (mouse)Mbd1
Organismmouse
Perturbation TypeKO
L1000CDS2 parameters
Directionreverse
Characteristic Direction parameters
Control SamplesGSM1269608, GSM1269609, GSM1269610
Perturbed SamplesGSM1269611, GSM1269612, GSM1269613
Tools used in the analysis
Dataset Accession
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE52547
Gene Expression Omnibus
Medullary Thymic Epitherlial Cell (mTEC) Gene Expression in MBD1 WT and KO Mice
7
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