Small molecules which mimic CD24 KD
Canned Analysis
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General Information
AccessionDCA00022753
TitleSmall molecules which mimic CD24 KD
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which mimic the gene expression signature induced by CD24 KD in the HT29 cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d206e6e467bea600fba484
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis CuratorApozar
CREEDS IDgene:2842
Cell TypeHT29
Gene Symbol (human)CD24
Organismhuman
Perturbation TypeKD
None{u'vals': [-0.0669983907165, -0.0645012802441, -0.0585908750106, -0.053863663988, -0.0528733563216, 0.0464822444043, 0.0462185112255, 0.0461017495122, -0.0442223030568, 0.0430079220061, 0.0422034622067, -0.0412612561461, -0.0408950205837, -0.0402695588483
L1000CDS2 parameters
Directionmimic
Characteristic Direction parameters
Control SamplesGSM377671, GSM377675
Perturbed SamplesGSM377676, GSM377677, GSM377678
Tools used in the analysis
Dataset Accession
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE15102
Gene Expression Omnibus
Response of pancreatic and colorectal cancer cells to CD24 down-regulation by monoclonal antibody or small interfering RNA
7
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