Small molecules which reverse ATXN1L KO
Canned Analysis
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General Information
AccessionDCA00022762
TitleSmall molecules which reverse ATXN1L KO
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which reverse the gene expression signature induced by ATXN1L KO in the hematopoietic stem cells cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d22244e467bea600fbb05a
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis CuratorKathaLahl
CREEDS IDgene:2848
Cell Typehematopoietic stem cells
Gene Symbol (human)ATXN1L
Gene Symbol (mouse)Atxn1l
Organismmouse
Perturbation TypeKO
L1000CDS2 parameters
Directionreverse
Characteristic Direction parameters
Control SamplesGSM1082321, GSM1082322, GSM1082323
Perturbed SamplesGSM1082324, GSM1082325
Tools used in the analysis
Dataset Accession
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Datasets used in the analysis
Keyword
Tool Name
GSE44285
Gene Expression Omnibus
Ataxin-1-like knock out effect on hematopoietic stem cells
7
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