Small molecules which mimic DNMT3B KO
Canned Analysis
FAIR Metrics
0 evaluations
General Information
AccessionDCA00022765
TitleSmall molecules which mimic DNMT3B KO
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which mimic the gene expression signature induced by DNMT3B KO in the HCT-116 cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d20ca4e467bea600fba70c
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis Curatorsara
CREEDS IDgene:2852
Cell TypeHCT-116
Gene Symbol (human)DNMT3B
Gene Symbol (mouse)Dnmt3b
Organismhuman
Perturbation TypeKO
L1000CDS2 parameters
Directionmimic
Characteristic Direction parameters
Control SamplesGSM85452, GSM85453, GSM85454
Perturbed SamplesGSM85460, GSM85461, GSM85462
Tools used in the analysis
Dataset Accession
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE3699
Gene Expression Omnibus
DNA-Methyltransferases (DNMT) knockouts
14
FAIR Evaluation
Sorry, you must be signed in to evaluate this object.