Small molecules which mimic IKBKB deletion
Canned Analysis
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General Information
AccessionDCA00022767
TitleSmall molecules which mimic IKBKB deletion
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which mimic the gene expression signature induced by IKBKB deletion in the peritoneal neutrophils cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d20c8ae467bea600fba700
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis Curatorames88cav
CREEDS IDgene:2853
Cell Typeperitoneal neutrophils
Gene Symbol (human)IKBKB
Gene Symbol (mouse)Ikbkb
Organismmouse
Perturbation Typedeletion
L1000CDS2 parameters
Directionmimic
Characteristic Direction parameters
Control SamplesGSM619276, GSM619277
Perturbed SamplesGSM619274, GSM619275
Tools used in the analysis
Dataset Accession
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE25211
Gene Expression Omnibus
IKKbeta deletion effect on neutrophils
7
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