Small molecules which reverse THOC5 KD
Canned Analysis
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General Information
AccessionDCA00022774
TitleSmall molecules which reverse THOC5 KD
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which reverse the gene expression signature induced by THOC5 KD in the HeLa cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d20c4de467bea600fba6e6
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis Curatorpdish
CREEDS IDgene:2858
Cell TypeHeLa
Gene Symbol (human)THOC5
Gene Symbol (mouse)Thoc5
Organismhuman
Perturbation TypeKD
L1000CDS2 parameters
Directionreverse
Characteristic Direction parameters
Control SamplesGSM1037857, GSM1037858
Perturbed SamplesGSM1037859, GSM1037860
Tools used in the analysis
Dataset Accession
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE42327
Gene Expression Omnibus
Genome-wide gene expression analysis in Thoc5- and CFIm68-depleted HeLa cells
14
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