Small molecules which mimic THOC1 KD
Canned Analysis
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General Information
AccessionDCA00022803
TitleSmall molecules which mimic THOC1 KD
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which mimic the gene expression signature induced by THOC1 KD in the HeLa cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d21abbe467bea600fbad3c
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis Curatorpdish
CREEDS IDgene:2872
Cell TypeHeLa
Gene Symbol (human)THOC1
Gene Symbol (mouse)Thoc1
Organismhuman
Perturbation TypeKD
L1000CDS2 parameters
Directionmimic
Characteristic Direction parameters
Control SamplesGSM669390, GSM669391, GSM669392
Perturbed SamplesGSM669393, GSM669394, GSM669395
Tools used in the analysis
Dataset Accession
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE27091
Gene Expression Omnibus
Expression profile of HeLa THOC1-depleted stable cell lines (HeTH-4)
7
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