Small molecules which reverse SRF KO
Canned Analysis
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General Information
AccessionDCA00022822
TitleSmall molecules which reverse SRF KO
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which reverse the gene expression signature induced by SRF KO in the aorta cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d22937e467bea600fbb36a
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis CuratorHollyWoodland
CREEDS IDgene:2884
Cell Typeaorta
Gene Symbol (human)SRF
Gene Symbol (mouse)Srf
Organismmouse
Perturbation TypeKO
L1000CDS2 parameters
Directionreverse
Characteristic Direction parameters
Control SamplesGSM850855, GSM850856, GSM850859, GSM850860
Perturbed SamplesGSM850857, GSM850858, GSM850861, GSM850862
Tools used in the analysis
Dataset Accession
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Datasets used in the analysis
Keyword
Tool Name
GSE34545
Gene Expression Omnibus
Early effects of Serum Response Factor (SRF) gene deletion on the vascular gene expression
7
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