Small molecules which reverse FGF21 KO
Canned Analysis
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General Information
AccessionDCA00022824
TitleSmall molecules which reverse FGF21 KO
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which reverse the gene expression signature induced by FGF21 KO in the liver cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d22a3be467bea600fbb3de
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis CuratorHollyWoodland
CREEDS IDgene:2887
Cell Typeliver
Gene Symbol (human)FGF21
Gene Symbol (mouse)Fgf21
Organismmouse
Perturbation TypeKO
L1000CDS2 parameters
Directionreverse
Characteristic Direction parameters
Control SamplesGSM1400262, GSM1400263, GSM1400264, GSM1400265
Perturbed SamplesGSM1400270, GSM1400271, GSM1400272, GSM1400273
Tools used in the analysis
Dataset Accession
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE58062
Gene Expression Omnibus
Triiodothyronine (T3) response in liver of FGF21 knockout mice
7
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