Small molecules which mimic TFAP2C Silencing - siRNA1
Canned Analysis
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General Information
AccessionDCA00022827
TitleSmall molecules which mimic TFAP2C Silencing - siRNA1
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which mimic the gene expression signature induced by TFAP2C Silencing - siRNA1 in the MCF-7 breast tumor cell line cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d2177de467bea600fbabd0
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis Curatorcadimo
CREEDS IDgene:2892
Cell TypeMCF-7 breast tumor cell line
Gene Symbol (human)TFAP2C
Gene Symbol (mouse)Tfap2c
Organismhuman
Perturbation TypeSilencing - siRNA1
L1000CDS2 parameters
Directionmimic
Characteristic Direction parameters
Control SamplesGSM388436, GSM388437, GSM388438
Perturbed SamplesGSM388424, GSM388425, GSM388426
Tools used in the analysis
Dataset Accession
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE15481
Gene Expression Omnibus
Activator protein-2gamma silencing effect on MCF-7 breast tumor cell line
42
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