Small molecules which reverse TFAP2C KD
Canned Analysis
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General Information
AccessionDCA00022836
TitleSmall molecules which reverse TFAP2C KD
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which reverse the gene expression signature induced by TFAP2C KD in the siRNA treated MCF-7 breast carcinoma cell line cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d1f68de467bea600fb9d94
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis Curatorgszeto
CREEDS IDgene:2968
Cell TypesiRNA treated MCF-7 breast carcinoma cell line
Gene Symbol (human)TFAP2C
Gene Symbol (mouse)Tfap2c
Organismhuman
Perturbation TypeKD
L1000CDS2 parameters
Directionreverse
Characteristic Direction parameters
Control SamplesGSM388433, GSM388434, GSM388435
Perturbed SamplesGSM388427, GSM388428, GSM388429
Tools used in the analysis
Dataset Accession
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Datasets used in the analysis
Keyword
Tool Name
GSE15481
Gene Expression Omnibus
Activator protein-2gamma silencing effect on MCF-7 breast tumor cell line
42
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