Small molecules which reverse ESR1 KO
Canned Analysis
FAIR Metrics
0 evaluations
General Information
AccessionDCA00022844
TitleSmall molecules which reverse ESR1 KO
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which reverse the gene expression signature induced by ESR1 KO in the uterus cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d21839e467bea600fbac26
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis CuratorHollyWoodland
CREEDS IDgene:2898
Cell Typeuterus
Gene Symbol (human)ESR1
Gene Symbol (mouse)Esr1
Organismmouse
Perturbation TypeKO
L1000CDS2 parameters
Directionreverse
Characteristic Direction parameters
Control SamplesGSM568946, GSM568947, GSM568948
Perturbed SamplesGSM1301143, GSM1301144, GSM1301145
Tools used in the analysis
Dataset Accession
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE53812
Gene Expression Omnibus
17-estradiol effect on uterus of uterine epithelial ER conditional knockout model: time course
7
FAIR Evaluation
Sorry, you must be signed in to evaluate this object.