Small molecules which mimic RUNX1 KO
Canned Analysis
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General Information
AccessionDCA00022845
TitleSmall molecules which mimic RUNX1 KO
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which mimic the gene expression signature induced by RUNX1 KO in the mammary gland luminal epithelial cells cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d2182de467bea600fbac20
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis CuratorHollyWoodland
CREEDS IDgene:2899
Cell Typemammary gland luminal epithelial cells
Gene Symbol (human)RUNX1
Gene Symbol (mouse)Runx1
Organismmouse
Perturbation TypeKO
L1000CDS2 parameters
Directionmimic
Characteristic Direction parameters
Control SamplesGSM1148294, GSM1148295, GSM1148296
Perturbed SamplesGSM1148297, GSM1148298, GSM1148299
Tools used in the analysis
Dataset Accession
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE47375
Gene Expression Omnibus
Microarray expression profiling study of Runx1-null and wild type luminal mammary epithelial cells
7
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