Small molecules which reverse DUSP5 KO
Canned Analysis
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General Information
AccessionDCA00022858
TitleSmall molecules which reverse DUSP5 KO
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which reverse the gene expression signature induced by DUSP5 KO in the embryonic fibroblasts cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d23a63e467bea600fbbaf8
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis CuratorHollyWoodland
CREEDS IDgene:2901
Cell Typeembryonic fibroblasts
Gene Symbol (human)DUSP5
Gene Symbol (mouse)Dusp5
Organismmouse
Perturbation TypeKO
L1000CDS2 parameters
Directionreverse
Characteristic Direction parameters
Control SamplesGSM1526936, GSM1526937, GSM1526938
Perturbed SamplesGSM1526939, GSM1526940, GSM1526941
Tools used in the analysis
Dataset Accession
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Datasets used in the analysis
Keyword
Tool Name
GSE62433
Gene Expression Omnibus
Deletion of DUSP5 affects the expression of a subset of TPA-inducible genes
7
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