Small molecules which mimic RAP1A KO
Canned Analysis
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General Information
AccessionDCA00022861
TitleSmall molecules which mimic RAP1A KO
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which mimic the gene expression signature induced by RAP1A KO in the HCT116 cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d23a34e467bea600fbbae4
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis CuratorHollyWoodland
CREEDS IDgene:2904
Cell TypeHCT116
Gene Symbol (human)RAP1A
Gene Symbol (mouse)Rap1a
Organismhuman
Perturbation TypeKO
L1000CDS2 parameters
Directionmimic
Characteristic Direction parameters
Control SamplesGSM1516754, GSM1516755, GSM1516756, GSM1516757, GSM1516758, GSM1516759
Perturbed SamplesGSM1516760, GSM1516761, GSM1516762, GSM1516763, GSM1516764, GSM1516765
Tools used in the analysis
Dataset Accession
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Datasets used in the analysis
Keyword
Tool Name
GSE61900
Gene Expression Omnibus
TALEN gene knockouts reveal no requirement for the shelterin protein Rap1 in telomere protection and length regulation
21
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