Small molecules which reverse RAP1A KO
Canned Analysis
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General Information
AccessionDCA00022864
TitleSmall molecules which reverse RAP1A KO
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which reverse the gene expression signature induced by RAP1A KO in the HT1080 cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d23a2de467bea600fbbae2
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis CuratorHollyWoodland
CREEDS IDgene:2905
Cell TypeHT1080
Gene Symbol (human)RAP1A
Gene Symbol (mouse)Rap1a
Organismhuman
Perturbation TypeKO
L1000CDS2 parameters
Directionreverse
Characteristic Direction parameters
Control SamplesGSM1516766, GSM1516767, GSM1516768, GSM1516769
Perturbed SamplesGSM1516770, GSM1516771, GSM1516772, GSM1516773
Tools used in the analysis
Dataset Accession
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Datasets used in the analysis
Keyword
Tool Name
GSE61900
Gene Expression Omnibus
TALEN gene knockouts reveal no requirement for the shelterin protein Rap1 in telomere protection and length regulation
21
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