Small molecules which reverse CXCL5 KO
Canned Analysis
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General Information
AccessionDCA00022868
TitleSmall molecules which reverse CXCL5 KO
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which reverse the gene expression signature induced by CXCL5 KO in the murine lung tissue cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d1fd20e467bea600fba034
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis CuratorHollyWoodland
CREEDS IDgene:2907
Cell Typemurine lung tissue
Gene Symbol (human)CXCL5
Organismmouse
Perturbation TypeKO
L1000CDS2 parameters
Directionreverse
Characteristic Direction parameters
Control SamplesGSM1060662, GSM1060664, GSM1060671, GSM1060673
Perturbed SamplesGSM1060663, GSM1060666, GSM1060672
Tools used in the analysis
Dataset Accession
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE43337
Gene Expression Omnibus
Impaired neutrophil recruitment in CXCL5 knockout mice during Mtb infection
7
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