Small molecules which reverse GNMT KO
Canned Analysis
FAIR Metrics
0 evaluations
General Information
AccessionDCA00022870
TitleSmall molecules which reverse GNMT KO
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which reverse the gene expression signature induced by GNMT KO in the liver cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d2019de467bea600fba230
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis CuratorHollyWoodland
CREEDS IDgene:2908
Cell Typeliver
Gene Symbol (human)GNMT
Gene Symbol (mouse)Gnmt
Organismmouse
Perturbation TypeKO
L1000CDS2 parameters
Directionreverse
Characteristic Direction parameters
Control SamplesGSM1538257, GSM1538258, GSM1538259, GSM1538260, GSM1538261
Perturbed SamplesGSM1538262, GSM1538263, GSM1538264, GSM1538265, GSM1538266
Tools used in the analysis
Dataset Accession
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE63027
Gene Expression Omnibus
Expression data from GNMT and MAT1A knockout models that develop all the stages of non-alcoholic fatty liver disease including hepatocellular carcinom...
28
FAIR Evaluation
Sorry, you must be signed in to evaluate this object.