Small molecules which mimic GNMT KO
Canned Analysis
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General Information
AccessionDCA00022871
TitleSmall molecules which mimic GNMT KO
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which mimic the gene expression signature induced by GNMT KO in the liver (8 months) cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d200f7e467bea600fba1e6
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis CuratorHollyWoodland
CREEDS IDgene:2909
Cell Typeliver (8 months)
Gene Symbol (human)GNMT
Gene Symbol (mouse)Gnmt
Organismmouse
Perturbation TypeKO
L1000CDS2 parameters
Directionmimic
Characteristic Direction parameters
Control SamplesGSM1538267, GSM1538268, GSM1538269, GSM1538270, GSM1538271
Perturbed SamplesGSM1538272, GSM1538273, GSM1538274, GSM1538275
Tools used in the analysis
Dataset Accession
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE63027
Gene Expression Omnibus
Expression data from GNMT and MAT1A knockout models that develop all the stages of non-alcoholic fatty liver disease including hepatocellular carcinom...
28
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