Small molecules which mimic ZMPSTE24 KD
Canned Analysis
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General Information
AccessionDCA00022889
TitleSmall molecules which mimic ZMPSTE24 KD
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which mimic the gene expression signature induced by ZMPSTE24 KD in the SCC-2 squamous cell carcinoma cells cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d2186ee467bea600fbac3c
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis Curatormaroulisv
CREEDS IDgene:3020
Cell TypeSCC-2 squamous cell carcinoma cells
Gene Symbol (human)ZMPSTE24
Gene Symbol (mouse)Zmpste24
Organismhuman
Perturbation TypeKD
L1000CDS2 parameters
Directionmimic
Characteristic Direction parameters
Control SamplesGSM1024470, GSM1024471
Perturbed SamplesGSM1024468, GSM1024469
Tools used in the analysis
Dataset Accession
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE41799
Gene Expression Omnibus
Transcriptional profiling of human cancer cell lines upon ZMPSTE24 silencing
28
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