Small molecules which mimic ZMPSTE24 KD
Canned Analysis
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General Information
AccessionDCA00022891
TitleSmall molecules which mimic ZMPSTE24 KD
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which mimic the gene expression signature induced by ZMPSTE24 KD in the A549 lung carcinoma cells cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d2293ee467bea600fbb36c
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis Curatormaroulisv
CREEDS IDgene:3021
Cell TypeA549 lung carcinoma cells
Gene Symbol (human)ZMPSTE24
Gene Symbol (mouse)Zmpste24
Organismhuman
Perturbation TypeKD
L1000CDS2 parameters
Directionmimic
Characteristic Direction parameters
Control SamplesGSM1024474, GSM1024475
Perturbed SamplesGSM1024472, GSM1024473
Tools used in the analysis
Dataset Accession
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE41799
Gene Expression Omnibus
Transcriptional profiling of human cancer cell lines upon ZMPSTE24 silencing
28
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