Small molecules which mimic ZMPSTE24 KD
Canned Analysis
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General Information
AccessionDCA00022893
TitleSmall molecules which mimic ZMPSTE24 KD
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which mimic the gene expression signature induced by ZMPSTE24 KD in the MDA-MB-231 breast adenocarcinoma cells cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d21880e467bea600fbac44
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis Curatormaroulisv
CREEDS IDgene:3022
Cell TypeMDA-MB-231 breast adenocarcinoma cells
Gene Symbol (human)ZMPSTE24
Gene Symbol (mouse)Zmpste24
Organismhuman
Perturbation TypeKD
L1000CDS2 parameters
Directionmimic
Characteristic Direction parameters
Control SamplesGSM1024478, GSM1024479
Perturbed SamplesGSM1024476, GSM1024477
Tools used in the analysis
Dataset Accession
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Datasets used in the analysis
Keyword
Tool Name
GSE41799
Gene Expression Omnibus
Transcriptional profiling of human cancer cell lines upon ZMPSTE24 silencing
28
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