Small molecules which reverse ZNF658 KD
Canned Analysis
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General Information
AccessionDCA00022896
TitleSmall molecules which reverse ZNF658 KD
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which reverse the gene expression signature induced by ZNF658 KD in the Caco-2 cells (siRNA1 knockdown) cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d212c3e467bea600fba9be
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis Curatorcadimo
CREEDS IDgene:2923
Cell TypeCaco-2 cells (siRNA1 knockdown)
Gene Symbol (human)ZNF658
Gene Symbol (mouse)Zfp735
Organismhuman
Perturbation TypeKD
L1000CDS2 parameters
Directionreverse
Characteristic Direction parameters
Control SamplesGSM1436126, GSM1436127, GSM1436128
Perturbed SamplesGSM1436123, GSM1436124, GSM1436125
Tools used in the analysis
Dataset Accession
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Datasets used in the analysis
Keyword
Tool Name
GSE59385
Gene Expression Omnibus
The zinc finger protein ZNF658 regulates the transcription of genes involved in zinc homeostasis and affects ribosome biogenesis through the zinc tran...
14
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