Small molecules which mimic HTT Mutation
Canned Analysis
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General Information
AccessionDCA00022901
TitleSmall molecules which mimic HTT Mutation
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which mimic the gene expression signature induced by HTT Mutation in the Brain cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d213e4e467bea600fbaa3c
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis Curatorlrallison
CREEDS IDgene:2926
Cell TypeBrain
Gene Symbol (human)HTT
Gene Symbol (mouse)Htt
Organismmouse
Perturbation TypeMutation
L1000CDS2 parameters
Directionmimic
Characteristic Direction parameters
Control SamplesGSM83870, GSM83874, GSM83876
Perturbed SamplesGSM83867, GSM83868
Tools used in the analysis
Dataset Accession
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE3621
Gene Expression Omnibus
Huntington's disease transgenic model: time course
24
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