Small molecules which reverse YAP1 KD
Canned Analysis
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General Information
AccessionDCA00022904
TitleSmall molecules which reverse YAP1 KD
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which reverse the gene expression signature induced by YAP1 KD in the MZ1774 human ccRCC cell line cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d21380e467bea600fbaa12
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis Curatorcadimo
CREEDS IDgene:2927
Cell TypeMZ1774 human ccRCC cell line
Gene Symbol (human)YAP1
Gene Symbol (mouse)Yap1
Organismhuman
Perturbation TypeKD
L1000CDS2 parameters
Directionreverse
Characteristic Direction parameters
Control SamplesGSM1213264, GSM1213265, GSM1213266, GSM1213267
Perturbed SamplesGSM1213260, GSM1213261, GSM1213262, GSM1213263
Tools used in the analysis
Dataset Accession
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE50053
Gene Expression Omnibus
YAP conveys an invasive phenotype to clear cell renal cell carcinoma cell lines via endothelin-2
7
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