Small molecules which reverse POU1F1 OE
Canned Analysis
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General Information
AccessionDCA00022906
TitleSmall molecules which reverse POU1F1 OE
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which reverse the gene expression signature induced by POU1F1 OE in the MCF-7 breast adenocarcinoma cell line cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d20dcde467bea600fba792
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis Curatorcadimo
CREEDS IDgene:2931
Cell TypeMCF-7 breast adenocarcinoma cell line
Gene Symbol (human)POU1F1
Gene Symbol (mouse)Pou1f1
Organismhuman
Perturbation TypeOE
L1000CDS2 parameters
Directionreverse
Characteristic Direction parameters
Control SamplesGSM1564340, GSM1564341
Perturbed SamplesGSM1564342, GSM1564343
Tools used in the analysis
Dataset Accession
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE64101
Gene Expression Omnibus
Pit-1 overexpression in the human breast adenocarcinoma MCF-7 cell line
7
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