Small molecules which mimic BRMS1 KD
Canned Analysis
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General Information
AccessionDCA00022907
TitleSmall molecules which mimic BRMS1 KD
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which mimic the gene expression signature induced by BRMS1 KD in the NSCLC (non-samll cell lung cancer) H1993 cells cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d20cfde467bea600fba734
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis Curatorcadimo
CREEDS IDgene:2935
Cell TypeNSCLC (non-samll cell lung cancer) H1993 cells
Gene Symbol (human)BRMS1
Gene Symbol (mouse)Brms1
Organismhuman
Perturbation TypeKD
L1000CDS2 parameters
Directionmimic
Characteristic Direction parameters
Control SamplesGSM1525721, GSM1525722
Perturbed SamplesGSM1525719, GSM1525720
Tools used in the analysis
Dataset Accession
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE62359
Gene Expression Omnibus
Loss of BRMS1 promotes a mesenchymal phenotype through regulation of Twist1
7
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