Small molecules which reverse MYD88 Deletion
Canned Analysis
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General Information
AccessionDCA00022914
TitleSmall molecules which reverse MYD88 Deletion
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which reverse the gene expression signature induced by MYD88 Deletion in the macrophages cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d204c1e467bea600fba392
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis Curatorames88cav
CREEDS IDgene:2943
Cell Typemacrophages
Gene Symbol (human)MYD88
Gene Symbol (mouse)Myd88
Organismmouse
Perturbation TypeDeletion
L1000CDS2 parameters
Directionreverse
Characteristic Direction parameters
Control SamplesGSM147166, GSM147167
Perturbed SamplesGSM147168, GSM147169
Tools used in the analysis
Dataset Accession
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE6376
Gene Expression Omnibus
MyD88 deficient macrophage response to zymosan
7
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