Small molecules which reverse OPTN KD
Canned Analysis
FAIR Metrics
0 evaluations
General Information
AccessionDCA00022924
TitleSmall molecules which reverse OPTN KD
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which reverse the gene expression signature induced by OPTN KD in the HeLa cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d22f3de467bea600fbb612
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis Curatorzero323
CREEDS IDgene:295
Cell TypeHeLa
Gene Symbol (human)OPTN
Gene Symbol (mouse)Optn
Organismhuman
Perturbation TypeKD
L1000CDS2 parameters
Directionreverse
Characteristic Direction parameters
Control SamplesGSM157215, GSM157216, GSM157217
Perturbed SamplesGSM157218, GSM157219, GSM157220
Tools used in the analysis
Dataset Accession
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Datasets used in the analysis
Keyword
Tool Name
GSE6819
Gene Expression Omnibus
Optineurin depletion
7
FAIR Evaluation
Sorry, you must be signed in to evaluate this object.