Small molecules which mimic FOXP3 Knockin
Canned Analysis
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General Information
AccessionDCA00022925
TitleSmall molecules which mimic FOXP3 Knockin
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which mimic the gene expression signature induced by FOXP3 Knockin in the CD4+ T cells cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d2265de467bea600fbb224
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis CuratorVICENTE
CREEDS IDgene:2950
Cell TypeCD4+ T cells
Gene Symbol (human)FOXP3
Gene Symbol (mouse)Foxp3
Organismmouse
Perturbation TypeKnockin
L1000CDS2 parameters
Directionmimic
Characteristic Direction parameters
Control SamplesGSM44979, GSM44982
Perturbed SamplesGSM44980, GSM44981
Tools used in the analysis
Dataset Accession
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE2389
Gene Expression Omnibus
CD4+ T cells expressing transcription factor Foxp3 and various amounts of CD25
7
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