Small molecules which reverse MTDH KD
Canned Analysis
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General Information
AccessionDCA00022934
TitleSmall molecules which reverse MTDH KD
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which reverse the gene expression signature induced by MTDH KD in the MCF-7 breast cancer cells cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d21267e467bea600fba996
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis Curatorcadimo
CREEDS IDgene:2954
Cell TypeMCF-7 breast cancer cells
Gene Symbol (human)MTDH
Gene Symbol (mouse)Mtdh
Organismhuman
Perturbation TypeKD
L1000CDS2 parameters
Directionreverse
Characteristic Direction parameters
Control SamplesGSM1425177, GSM1425178, GSM1425179
Perturbed SamplesGSM1425180, GSM1425181, GSM1425182
Tools used in the analysis
Dataset Accession
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE59055
Gene Expression Omnibus
A newly identified spliced isoform of metadherin differently regulates the global transcriptomic profile in MCF-7 breast cancer cells
7
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