Small molecules which mimic NOTCH1 OE
Canned Analysis
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General Information
AccessionDCA00022941
TitleSmall molecules which mimic NOTCH1 OE
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which mimic the gene expression signature induced by NOTCH1 OE in the Prostate luminal epithelial cells cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d20e00e467bea600fba7a8
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis Curatorcadimo
CREEDS IDgene:2958
Cell TypeProstate luminal epithelial cells
Gene Symbol (human)NOTCH1
Gene Symbol (mouse)Notch1
Organismmouse
Perturbation TypeOE
L1000CDS2 parameters
Directionmimic
Characteristic Direction parameters
Control SamplesGSM1280856, GSM1280857, GSM1280858, GSM1280859
Perturbed SamplesGSM1280860, GSM1280861, GSM1280862
Tools used in the analysis
Dataset Accession
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE53036
Gene Expression Omnibus
Gene expression profiling of mouse prostate over-expressing the Notch1 intracellular domain.
7
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