Small molecules which reverse MYOC OE
Canned Analysis
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General Information
AccessionDCA00022946
TitleSmall molecules which reverse MYOC OE
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which reverse the gene expression signature induced by MYOC OE in the retina cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d1fe22e467bea600fba0a6
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis Curatorzero323
CREEDS IDgene:296
Cell Typeretina
Gene Symbol (human)MYOC
Gene Symbol (mouse)Myoc
Organismmouse
Perturbation TypeOE
L1000CDS2 parameters
Directionreverse
Characteristic Direction parameters
Control SamplesGSM32153, GSM32154
Perturbed SamplesGSM32155, GSM32156
Tools used in the analysis
Dataset Accession
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE1835
Gene Expression Omnibus
Myocilin over-secretion effect on the retina
7
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