Small molecules which mimic PTEN Deletion
Canned Analysis
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General Information
AccessionDCA00022947
TitleSmall molecules which mimic PTEN Deletion
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which mimic the gene expression signature induced by PTEN Deletion in the HCT116 cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d1f731e467bea600fb9dda
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis Curatorames88cav
CREEDS IDgene:2960
Cell TypeHCT116
Gene Symbol (human)PTEN
Gene Symbol (mouse)Pten
Organismhuman
Perturbation TypeDeletion
L1000CDS2 parameters
Directionmimic
Characteristic Direction parameters
Control SamplesGSM144204, GSM144205, GSM144206
Perturbed SamplesGSM144202, GSM144203
Tools used in the analysis
Dataset Accession
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE6263
Gene Expression Omnibus
PTEN deletion mutation effect on colon cancer cells
14
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