Small molecules which reverse MIR210 KD
Canned Analysis
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General Information
AccessionDCA00022958
TitleSmall molecules which reverse MIR210 KD
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which reverse the gene expression signature induced by MIR210 KD in the Human Umbilical Vein Endothelial Cells (HUVEC) transfected with Locked Nucleic Acid (LNA) oligonucleotides against miR-210 or a control scramble sequence cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d21920e467bea600fbac8a
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis Curatorgszeto
CREEDS IDgene:2972
Cell TypeHuman Umbilical Vein Endothelial Cells (HUVEC) transfected with Locked Nucleic Acid (LNA) oligonucleotides against miR-210 or a control scramble sequence
Gene Symbol (human)MIR210
Organismhuman
Perturbation TypeKD
L1000CDS2 parameters
Directionreverse
Characteristic Direction parameters
Control SamplesGSM424765, GSM424766, GSM424767
Perturbed SamplesGSM424768, GSM424769, GSM424770
Tools used in the analysis
Dataset Accession
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE16962
Gene Expression Omnibus
Effect of mir-210 overexpression or down-modulation on human umbilical vein cells
14
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