Small molecules which reverse IKBKB expression of a constitutively active allele of the IÎ&ord

General Information

Accession	DCA00022962
Title	Small molecules which reverse IKBKB expression of a constitutively active allele of the IÎ&ord
Description	The L1000 database was queried in order to identify small molecule perturbations which reverse the gene expression signature induced by IKBKB expression of a constitutively active allele of the IÎ&ord in the Ramos cells; cell type: human Burkitt lymphoma; dsmz no.: ACC 603 origin: established from the ascitic fluid of a 3-year-old boy with American-type Burkitt lymphoma in 1972; cells were described to be EBV-negative but EBV infectible, to carry the (8;14) translocation and p53 mutations cell type.
Analysis URL	http://amp.pharm.mssm.edu/L1000CDS2/#/result/58d21929e467bea600fbac8e
Upload Date	September 20, 2017
Uploader	maayanlab

Metadata

Analysis Curator	gszeto
CREEDS ID	gene:2974
Cell Type	Ramos cells; cell type: human Burkitt lymphoma; dsmz no.: ACC 603 origin: established from the ascitic fluid of a 3-year-old boy with American-type Burkitt lymphoma in 1972; cells were described to be EBV-negative but EBV infectible, to carry the (8;14) t
Gene Symbol (human)	IKBKB
Gene Symbol (mouse)	Ikbkb
Organism	human
Perturbation Type	expression of a constitutively active allele of the IÎ&ord