Small molecules which mimic SOX2 KO
Canned Analysis
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General Information
AccessionDCA00022989
TitleSmall molecules which mimic SOX2 KO
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which mimic the gene expression signature induced by SOX2 KO in the Papilloma tumour epithelial cells cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d22fd0e467bea600fbb654
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis Curatorcadimo
CREEDS IDgene:2990
Cell TypePapilloma tumour epithelial cells
Gene Symbol (human)SOX2
Gene Symbol (mouse)Sox2
Organismmouse
Perturbation TypeKO
L1000CDS2 parameters
Directionmimic
Characteristic Direction parameters
Control SamplesGSM1342598, GSM1342601, GSM1342602
Perturbed SamplesGSM1342599, GSM1342600, GSM1342603
Tools used in the analysis
Dataset Accession
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Datasets used in the analysis
Keyword
Tool Name
GSE55738
Gene Expression Omnibus
Expression data from chemically-induced skin papillomas (benign tumours)
7
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