Small molecules which reverse HSPB8 KO
Canned Analysis
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General Information
AccessionDCA00023000
TitleSmall molecules which reverse HSPB8 KO
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which reverse the gene expression signature induced by HSPB8 KO in the Heart (left ventricles) cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d22f4fe467bea600fbb61a
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis CuratorJuliana
CREEDS IDgene:2996
Cell TypeHeart (left ventricles)
Gene Symbol (human)HSPB8
Gene Symbol (mouse)Hspb8
Organismmouse
Perturbation TypeKO
L1000CDS2 parameters
Directionreverse
Characteristic Direction parameters
Control SamplesGSM603058, GSM603059, GSM603060
Perturbed SamplesGSM603061, GSM603062, GSM603063
Tools used in the analysis
Dataset Accession
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE24489
Gene Expression Omnibus
Effect of H11 Kinase/Hsp22 deletion in response to cardiac stress
7
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