Small molecules which reverse HDC KO
Canned Analysis
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General Information
AccessionDCA00023010
TitleSmall molecules which reverse HDC KO
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which reverse the gene expression signature induced by HDC KO in the myeloid-derived suppressor cell from bone marrow cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d224c1e467bea600fbb16e
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis CuratorJuliana
CREEDS IDgene:3001
Cell Typemyeloid-derived suppressor cell from bone marrow
Gene Symbol (human)HDC
Gene Symbol (mouse)Hdc
Organismmouse
Perturbation TypeKO
L1000CDS2 parameters
Directionreverse
Characteristic Direction parameters
Control SamplesGSM575704, GSM575705
Perturbed SamplesGSM575706, GSM575707
Tools used in the analysis
Dataset Accession
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE23502
Gene Expression Omnibus
Differentially expressed genes of CD11b+Gr-1+ myeloid cells
14
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