Small molecules which mimic HDC KO
Canned Analysis
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General Information
AccessionDCA00023011
TitleSmall molecules which mimic HDC KO
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which mimic the gene expression signature induced by HDC KO in the myeloid-derived suppressor cell from colon tumor cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d224b5e467bea600fbb168
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis CuratorJuliana
CREEDS IDgene:3002
Cell Typemyeloid-derived suppressor cell from colon tumor
Gene Symbol (human)HDC
Gene Symbol (mouse)Hdc
Organismmouse
Perturbation TypeKO
L1000CDS2 parameters
Directionmimic
Characteristic Direction parameters
Control SamplesGSM575708, GSM575709
Perturbed SamplesGSM575710, GSM575711
Tools used in the analysis
Dataset Accession
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE23502
Gene Expression Omnibus
Differentially expressed genes of CD11b+Gr-1+ myeloid cells
14
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