Small molecules which mimic TCF7 KO
Canned Analysis
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General Information
AccessionDCA00023025
TitleSmall molecules which mimic TCF7 KO
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which mimic the gene expression signature induced by TCF7 KO in the CD8 memory T-cell cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d22962e467bea600fbb37c
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis CuratorJuliana
CREEDS IDgene:3010
Cell TypeCD8 memory T-cell
Gene Symbol (human)TCF7
Organismmouse
Perturbation TypeKO
L1000CDS2 parameters
Directionmimic
Characteristic Direction parameters
Control SamplesGSM520717, GSM520718, GSM520719
Perturbed SamplesGSM520720, GSM520721, GSM520722
Tools used in the analysis
Dataset Accession
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE20754
Gene Expression Omnibus
Expression data from WT and TCF-1-deficient memory CD8 T cells
7
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