Small molecules which mimic GFI1B KO
Canned Analysis
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General Information
AccessionDCA00023031
TitleSmall molecules which mimic GFI1B KO
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which mimic the gene expression signature induced by GFI1B KO in the Hematopoietic stem cells (Cd150+, Cd48-, Lin-, Sca+, c-kit+) cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d2297ce467bea600fbb388
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis CuratorJuliana
CREEDS IDgene:3013
Cell TypeHematopoietic stem cells (Cd150+, Cd48-, Lin-, Sca+, c-kit+)
Gene Symbol (human)GFI1B
Gene Symbol (mouse)Gfi1b
Organismmouse
Perturbation TypeKO
L1000CDS2 parameters
Directionmimic
Characteristic Direction parameters
Control SamplesGSM518397, GSM518398, GSM518399
Perturbed SamplesGSM518400, GSM518401, GSM518402
Tools used in the analysis
Dataset Accession
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE20655
Gene Expression Omnibus
Effect of loss of Gfi1b on hematopietic stem cells
7
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