Small molecules which reverse MAP3K8 KO
Canned Analysis
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General Information
AccessionDCA00023036
TitleSmall molecules which reverse MAP3K8 KO
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which reverse the gene expression signature induced by MAP3K8 KO in the bone marrow derived macrophages (not activated) cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d22948e467bea600fbb372
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis Curatormaroulisv
CREEDS IDgene:3019
Cell Typebone marrow derived macrophages (not activated)
Gene Symbol (human)MAP3K8
Gene Symbol (mouse)Map3k8
Organismmouse
Perturbation TypeKO
L1000CDS2 parameters
Directionreverse
Characteristic Direction parameters
Control SamplesGSM1175312, GSM1175313
Perturbed SamplesGSM1175314, GSM1175315
Tools used in the analysis
Dataset Accession
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE48338
Gene Expression Omnibus
Lipopolysaccharide effect on tumor progression locus 2 kinase-deficient macrophages
7
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