Small molecules which reverse KDM1A KD
Canned Analysis
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General Information
AccessionDCA00023040
TitleSmall molecules which reverse KDM1A KD
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which reverse the gene expression signature induced by KDM1A KD in the 3T3-L1 preadipocytes cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d20178e467bea600fba220
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
CREEDS IDgene:3082
Cell Type3T3-L1 preadipocytes
Gene Symbol (human)KDM1A
Gene Symbol (mouse)Kdm1a
Organismmouse
Perturbation TypeKD
L1000CDS2 parameters
Directionreverse
Characteristic Direction parameters
Control SamplesGSM624121, GSM624122, GSM624125, GSM624126, GSM624127
Perturbed SamplesGSM624123, GSM624124, GSM624128, GSM624129, GSM624130
Tools used in the analysis
Dataset Accession
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Datasets used in the analysis
Keyword
Tool Name
GSE25423
Gene Expression Omnibus
Histone demethylase KDM1A deficiency effect on 3T3-L1 preadipocytes: time course
26
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