Small molecules which mimic ATXN7 OE
Canned Analysis
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General Information
AccessionDCA00023045
TitleSmall molecules which mimic ATXN7 OE
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which mimic the gene expression signature induced by ATXN7 OE in the Retinas of R7E cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d21877e467bea600fbac40
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis Curatorames88cav
CREEDS IDgene:3023
Cell TypeRetinas of R7E
Gene Symbol (human)ATXN7
Gene Symbol (mouse)Atxn7
Organismmouse
Perturbation TypeOE
L1000CDS2 parameters
Directionmimic
Characteristic Direction parameters
Control SamplesGSM84313, GSM84314, GSM84315, GSM84316
Perturbed SamplesGSM84333, GSM84334, GSM84335, GSM84336, GSM84337, GSM84338
Tools used in the analysis
Dataset Accession
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE3634
Gene Expression Omnibus
Polyglutamine expansion disease model: retina
7
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