Small molecules which mimic PIK3CA KD
Canned Analysis
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General Information
AccessionDCA00023063
TitleSmall molecules which mimic PIK3CA KD
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which mimic the gene expression signature induced by PIK3CA KD in the H69 cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d21f0ce467bea600fbaef0
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis CuratorApozar
CREEDS IDgene:3033
Cell TypeH69
Gene Symbol (human)PIK3CA
Gene Symbol (mouse)Pik3ca
Organismhuman
Perturbation TypeKD
L1000CDS2 parameters
Directionmimic
Characteristic Direction parameters
Control SamplesGSM996643, GSM996644, GSM996645
Perturbed SamplesGSM996649, GSM996650, GSM996651
Tools used in the analysis
Dataset Accession
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE40564
Gene Expression Omnibus
Targeting the Phosphoinositide 3-Kinase p110 Isoform Impairs Cell Proliferation, Survival and Tumor Growth in Small Cell Lung Cancer
7
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