Small molecules which reverse CLDN1 KD
Canned Analysis
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General Information
AccessionDCA00023068
TitleSmall molecules which reverse CLDN1 KD
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which reverse the gene expression signature induced by CLDN1 KD in the A549 cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d21f07e467bea600fbaeee
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis CuratorApozar
CREEDS IDgene:3035
Cell TypeA549
Gene Symbol (human)CLDN1
Gene Symbol (mouse)Cldn1
Organismhuman
Perturbation TypeKD
L1000CDS2 parameters
Directionreverse
Characteristic Direction parameters
Control SamplesGSM799186, GSM799187, GSM799188, GSM799189, GSM799190, GSM799191
Perturbed SamplesGSM799192, GSM799193, GSM799194, GSM799195, GSM799196, GSM799197
Tools used in the analysis
Dataset Accession
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE32254
Gene Expression Omnibus
Claudin 1 mediates TNF-induced gene expression and cell migration in human lung carcinoma cells
7
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